HOW DOES CBD WORK WITH (X) MEDICATION?
CBD has been shown in large quantities to interact with your CYP450, essentially “deactivating” it. This obviously is not good as it can cause adverse reactions with medications, especially anxiolytics. (Heighten/weaken the strength, or activation of side effects like nausea, etc)
DOES CBD OIL MAKE YOU NAUSEOUS?
People sometimes feel this way due to the carrier oil used, make sure you eat before taking it- You may be sensitive to the coconut oil or carrier oil.
WHAT’S FULL-SPECTRUM VS ISOLATE?
Full-spectrum means the product contains THC and other cannabinoids, not just CBD. Isolate means it’s solely CBD or the listed cannabinoid. (CBN, CBG, etc)
WILL CBD MAKE ME POSITIVE ON DRUG TESTS?
See above. If Full-Spectrum it’s fully possible to test positive. If it’s isolate, it shouldn’t.
CBD WITH KEPPRA? DEPAKOTE? DIAZEPAM? CLOBAZAM? (INSERT ANTICONVULSANT HERE)
Advise caution when mixing any anticonvulsant with CBD as it can pose risks as mentioned earlier with CYP450- Talk to your Neurologist/Epileptologist before committing. (Or ask Dr Krishna!)
HOW DOES OMEGA-3 WORK WITH CBD?
Essentially it’s said that Omega-3 deficiencies do have a correlation with low CB1 response, especially being that omega-3 deficiencies are a fairly common occurrence with the American diet. Low Omega-3 can lead to seasonal affective disorder – “Using mice, the study found that a deficiency in Omega-3 caused presynaptic CB1 receptors to uncouple from their effector G proteins, essentially disabling them. This dietary-induced impairment of CB1 function adversely affected emotional behaviour.”, So essentially when Omega 3 is in place it’s holding the CB receptors, preventing de-coupling. So with Omega-3 usage with CBD, you are ensuring the CB receptors are not degraded, or decoupled, thus ensuring maximum potential benefit. There’s a good study about this and MDD here: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC533861/
HOW DO I KNOW IF IT IS WORKING?
Typically CBD is shown as ‘working’ per symptomatic relief. It will not cure your ailments, merely treat symptoms- nausea, pain, anxiety, depression, etc. Compare yourself prior to taking it, and after. You should have relief from what you’re looking to address – if not, try a higher dosage. The oils also help women for menstrual cramps.
AM I DOING THIS RIGHT? I DON’T FEEL THE EFFECT I THOUGHT I WAS GOING TO FEEL?
Due to CB1/CB2 cluster sizes, everyone experiences CBD slightly differently. If you’re expecting something like a THC high, or even alcohol inebriation- you’re not thinking about it right. Ideally, you will feel almost perfectly normal, just without the given symptom you’re looking to address. E.g. Pain > No Pain.